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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b46986d8a17357e32470d498c1881eccfdd09ae21c170c66e87b2ec3f812599' 
  AND token = 'BeIVXnh3uuLriOZ2IQmV5N3758drCoYl0SBPJh8k0n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}