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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1963eab05b5af7dcf05e69203426f454659e99dc26f61a8eba4c89268cf5a7f6' 
  AND token = 'P2BHHrglhr08YN+91vAmo/53dBBTfsN+wbTu1WLcW9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}