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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f085476cbc91e8e029700d5db31ec6406efe72a88c59af6e9fb8f4a345f990' 
  AND token = 'kQoAb8eqsO7e+i6aF8vhokLeCvLPoMLU8+x7J4AO0vY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}