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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d21d50ef710dfcfe92bb1cab434acda46e1ec5e49b51c6504328cdb2561d1ef' 
  AND token = '8i72pTytUUFRYzin3eR1iZo1qqeDxzWam4hzykHCbG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}