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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fc0c359b7bcb98ad8e8d0afe95d8cf92d73c4d648afa23b75117f27993a9435' 
  AND token = 'bGTWaVkvyl5dFTN1gPwHMtNbFIhO6kUymlzv8CmEGIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}