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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9010c4b06787c632e580411026dadfe0f95ed76fd8fff523d456f66a28c03ec' 
  AND token = 'TEeb6WycIEEIy2P+1mJhazZ9zQHsgc/l3595rzO82lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}