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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0387f5e19e78ab4aedec9ce44c90356c8f863a17749070f5b59a9eaad6efebd' 
  AND token = 'NCwM+z662eOV8B++QtnUoil5+ZJmUO9KdU1I0RYyXUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}