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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e943f79cae7120f38527c163098aaf272c89f9aa6863b11df5aea813eedc4ecd' 
  AND token = 'j3z/oIfU2/5+WG5eu0ync10/1aTcSKHTpSEt0FtPhGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}