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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '320eba1244bab27b90c86f3a1251ff57146bb91ea42d2388a89be540dc01be9c' 
  AND token = 'HQ1fpsIMNYk/7r0FQsEwFlMMoPjUTI80pZEMBX4c+T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}