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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7c62d0e97c1bb5eb61641991c92756f005d99eabdd426d97f1365f9a07d5e02' 
  AND token = 'TFg1uAoSROUlYQ/FUm0Z+L8IWGa18eqMMRT1lBrpEKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}