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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f3086a46ecd9a2276cf902d348634c69c7fc367e2054749fae508ce036a3b0' 
  AND token = 'rkJaQ+CnE2dl6GKytP/lkXynlX1TAYSlm4VdK61Je78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}