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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '948726b9ac11a74c45d9124d7f2392c93e9b9d28a394cf2649af9d8515fee077' 
  AND token = 'YepI37MVdluRcZo1xrR0vzRoTge3+LUupluT2j9PnxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}