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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b44054b4e159409854dcb6c969db876371d4f11af079dc9e0ff33165d8e0450b' 
  AND token = 'gWk/j4rUXRW+HwhjDMUea8QNLWGzO5yTIsw1eEumzYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}