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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2010170990e52f7fb2664a3d43e0f9cf5066ae97b9694cdc68d10a9383ce6fe' 
  AND token = 's0UjeBawm7IdM01PhV3JMzBM14xmPbpqMZR7oK+lL0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}