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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106e5cba02b7a8d13c3c1e18ca3f18796d89896d0ae4241f5edc5733eea38803' 
  AND token = 'mwwzB3/MTUnq4qlxADr2EGHSidyxxsKt3fDNbXyCaaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}