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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcdfb3ed4e3b584e61640992d4a1509d5e1331a7ef23a14f02eaa28460f96936' 
  AND token = 'z8n96V+YMkgDMHqKYM/NuoaOiYrTH2Yds2D49o1Q6wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}