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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c1527df527ff8b8602dc80782b0b12d64b6e36ef63496123fee3a27e7272c1f' 
  AND token = 'VG/W4XMcMN0qcyuUp5GqXigEt7jMCfsHOSOeKS8DoTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}