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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66fd2118c44945d431f370003f59363071b03de0625f9fa1cc8449ab3319f5fe' 
  AND token = 'F8Hi96R1OIbo883oYmgTmAZzZ2f65CWF8iI8vwEP5Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}