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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca563976da2c151566dac4bf4b33e29989d05100c92283713c0da6bf6dedb2b' 
  AND token = '78AItGd6h9ANY/44abrxMzmSKRkXvB5G3Ul5YOdm1Bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}