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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f71508ca067337eeed34c1e667f6f7d6c4b66bfce5625bb43e65e4b4ba71a5' 
  AND token = 'l5A0mCFxmIPDOdaJi46VlijWWGdwUOr4l3eDlOID7B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}