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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d33e62bbbfbe8a92ef8ac50691bbba8a14d5612f49d67684c22626876151e7e' 
  AND token = 'tX8lar/93QfHskSRO5ZMIVSPLRmQ5Htbly+LoW4SzBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}