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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca204635f813999715239e11658e2a8912b6510359c223e4b334b7f76158718e' 
  AND token = 'DZd8JUs+MFBwevOnbqe0viWD/+1iwfrYWfG2XxDZUyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}