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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '742dc75e2b70d8a7ec94e839017346a93f316fe91490df79cdc564d010c5dbb6' 
  AND token = 'DoQ7kHpfMWEo3bRi6j18AcKokUx3m0qb3vmLTK9lb3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}