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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6f943ad6ff6198eef6119097a8a88acf821b4ec66f8756d0821d69f6e8d102' 
  AND token = 'LXeDqwtnk1pGs3t1E8+G8fnok1Fh+coiRdZoG4PlW/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}