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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f60a6a09f7aa38890bff2da45b2c82373829ac73a0817a9d8f9d2983b460fc97' 
  AND token = 'o7LxX+i4MAN2nhngqq4XvAG5EEnZzxnnYmaXaVWN1GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}