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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '160aa07e640e4a2b358fa8283df7c5056599f6b4000f8e0dbfe8feb898521da6' 
  AND token = 'N1JWIHCbdfBQYYmojtVx7kYbvg21D4CTdIKr0rznlEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}