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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd56148789aa48d4998eded43655ee0bf7dabfb7d2d9005e893358cd9573734' 
  AND token = 'D6ltnskJnbq3z/Md1N4kgzxX5ootjabKb9udrvk8Ws0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}