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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff1d6ed3299a6860e98fe021be2787e9feffcc22e1a1ae26c1d281845a66e33' 
  AND token = 'f4DC/CLrHPdrepn/cmU6AQl1BT08pR8HYCOfFDyjQ2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}