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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1d63c54ad6986ebcca89d8ab898fa07b000de7fd1b2e0b363d0a45433e6a6af' 
  AND token = 'NUYtUa+M6+ddFhOnLpU2Uwal/5cwyp7VPROh7UrnkT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}