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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef499942e42e98cf20aba4da4d2738fab1b54d1296a18bbe556a62a7ddf8d999' 
  AND token = '9o97Ns94Tgx6VAw2NtLn+GbsTJk26mZD0j6WC4ogB0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}