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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d11fddb20c3f2dd8ad4e03c6356d68346d59b873155a2f6a459124f5c6fa5a4' 
  AND token = 'e2ZaJIaMkLF0CO1lKSp+uC6m0f6R1cz3DsrwUvfqixs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}