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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1b67a9296cb552f5edab62e031704b2e9816b8157514cf2613e8ec575b5a2e1' 
  AND token = 'nebXDGvNQkGliaQBqP59tgs0u26THVXdwvqpFNWTAHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}