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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '953cb354f989bb4001c91ca75db904a2d75f5b02de1aa4bbb62ca43b5484b54c' 
  AND token = 'WBqKwFWMs9tlTIu7MhM2OLyLTmFS/0Ekh5BzSF6FFEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}