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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22b462ac2d65ef6cea52016c1d05f15f603ec8fc2e74a4afdb05a7fcd737b72' 
  AND token = 'IkbbcJ0dR9dvnds1lmovpS7FoV8xpWa2CFqH3Xj/boA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}