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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed4ca095c831a6847c02d646293fc95b03fc60d153d1e5abc70f4ec206656d2' 
  AND token = '+Z6xZqYA4jDV9/O40A+9KD88xwptIAxv3OQSITWzk/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}