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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c11b67a339100da969f0a5aca10ac901be470b27f3d18f382a4eeae1f8a6107' 
  AND token = '2IEtMYYowQajpwzAyzP+3QGzy3OqEBSb21o89uLmhFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}