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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '565e8d3406b435fc2491835837f76f753c16356fe17e511c324bc79893294255' 
  AND token = 'FriwlOZofcP30Wb2c20ZxhK8s3DtycUTAgseHreVOZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}