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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95533c53c6ee6e9ae0186e9e215e913fbc2d3e18139cb5a66526cd0906615561' 
  AND token = 'RYwNN2CI4YCjAlB4qZ/74qp8bgpCk3nDu1gONBXOsV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}