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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38d543bfe78222262cb997be57d1bbf1bf4c0a5a93866aa54f415182e55cb23' 
  AND token = '8Y2Y6eiWejxgu8vp8Q+kiebbs/REgGSlvRINkA9xcnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}