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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4445d8e69bfc7735637dd236f9aa8db311deb3258ae31c2146828914901070a1' 
  AND token = 'I452YRcoYK8m2znYXLNjG1mdO4KS+xcVUsP95Q6RbmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}