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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8fba6393c6fbd41b0b2770b76e94b40636ef7b04853f234877cdcf9514c96e' 
  AND token = '1UavWiAw2LQiVPfvsnunKGqLg2rk8D02XgHEIQCvP5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}