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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7c27b795e0287d1578d87e72c7f2fbb0f5e0c2cb4166f256ac1bbcfda8e019' 
  AND token = 'i/93d+ZibOVi2JqlvSkCS9IVKgNpoZ29+0MT8TftG4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}