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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb0929ff53278f067cdc79e6347c3def68c673b9ec7cf2efc5fc1cb4a13beb1e' 
  AND token = 'Yjvvn/FW0K3IUcEx5JTHOsw+zNsbIjpd4D6IJMLrY24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}