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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273d43135c12f1345b1ebddfc76414c4107acf258cd9ef91ddfd3cdf81a46b84' 
  AND token = 'tdnly/ZXu+Fa5i/I2S+9zFrIBkvUfgRXl7V+q3AfxZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}