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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd4ca8a197bc90376325765ed0163e9669f98035ebe82e8544106dc40a5110fa' 
  AND token = 'ZxtmObu/KRdmPZWeghy0iBLc5u3qfG9r6TUdf7YysSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}