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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1564b26e56e3209a5dea167db0bfe2265c697e6c112924a4e7f80a07de88a3a5' 
  AND token = 'KcazyHZ5fG7kK6IQIWlG64CI5brrRdgrLe4gLX+QmZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}