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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1568dcc40f0dd6cfac017a4280a5190f0c738b27695937bdbf1c49f9e0634a32' 
  AND token = 'H6KRS+UI58GIaBKskhSgWcuBa81L2m9puuOb0Ao2BQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}