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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0381d3b205e617acb7a2f12c0d346a7469949e23ef8b44dab4f460d007cbcfd4' 
  AND token = 'l+apmHdtm4NHM0Pa16cEr6ayXF3rF5CXg6ABQ/9pXUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}