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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21bfdd437ec6b1131732f20fc37cce49e80bbb46fb6c2b88ea04c073b1372e0' 
  AND token = 'knjvAghOPgg9n9koc5r828QNcTOPvJKTz64iHGXfbNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}