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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f97faf3bc140474780f84e0051d6abd485baf6a049665d50208624b1ee0788' 
  AND token = 'emiJ78Wk7Aqzo7lee4oR2KzhRDZCyz2x2KER3FeTeME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}